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Brillouin Imaging: BOE 5, 2202 –
Coppola, S., T. Schmidt, G. Ruocco, and G. Antonacci. 2019. “Quantifying cellular forces and biomechanical properties by correlative micropillar traction force and Brillouin microscopy”. Biomed. Opt. Express 10(5):2202-2212. [DOI] [pdf] Cells sense and respond to external physical forces and substrate … Continue reading
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GR mobility: JCS 132, 2019
Keizer VIP, Coppola S, Houtsmuller AB, Geverts B, van Royen ME, Schmidt T, Schaaf MJM. Repetitive switching between DNA-binding modes enables target finding by the glucocorticoid receptor. J Cell Sci. 2019 Feb 25;132(5). pii: jcs217455. [DOI] [pdf]
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hERG and cytoskeleton in PDAC: Cancer 23, 2019
Manoli S, Coppola S, Duranti C, Lulli M, Magni L, Kuppalu N, Nielsen N, Schmidt T, Schwab A, Becchetti A, Arcangeli A. The Activity of Kv 11.1 Potassium Channel Modulates F-Actin Organization During Cell Migration of Pancreatic Ductal Adenocarcinoma Cells. … Continue reading
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Force vs shape: Phys.Rev.Lett. 121, 2018
Pomp W, Schakenraad K, Balcıoğlu HE, van Hoorn H, Danen EHJ, Merks RMH, Schmidt T, Giomi L. Cytoskeletal Anisotropy Controls Geometry and Forces of Adherent Cells. Phys Rev Lett. 2018 Oct 26; 121(17):178101. [DOI] [pdf]
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Mechanopharmacology: DRU, 31, 2017
Coppola S, Carnevale I, Danen EHJ, Peters GJ, Schmidt T, Assaraf YG, Giovannetti E (2017) A mechanopharmacology approach to overcome chemoresistance in pancreatic cancer., Drug Resist. Updat., 31, 43-51. [DOI] [pdf] Pancreatic ductal adenocarcinoma (PDAC) is a highly chemoresistant malignancy. … Continue reading
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