Category Archives: Publications

Alessandro’s and Cecilia’s paper in which they investigated how chemoresistance modulates the mechanical phenotype of cells.   Altered Mechanobiology of PDAC Cells with Acquired Chemoresistance to Gemcitabine and Paclitaxel. Alessandro Gregori, Cecilia Bergonzini, Mjriam Capula, Rick Rodrigues de Mercado, Erik … Continue reading →

“Hexanematic crossover in epithelial monolayers depends on cell adhesion and cell density” Julia Eckert, Benoît Ladoux, René-Marc Mège, Luca Giomi & Thomas Schmidt Changes in tissue geometry during developmental processes are associated with collective migration of cells. Recent experimental and … Continue reading →

Integrin alpha-2 popped up in a screen of aggressive and chemoresistant PDAC cancers. In this study of Alessandro and Cecilia we validated the results we obtained in the RNA screen with various methods. Again we find a correlation between cell … Continue reading →

We developed a novel methodology to count the number of molecules in a STORM image. That allowed us to address the stoichiometry of adhesion proteins in focal adhesions. It appeared that the stoichiometry in FAK is independent on the force … Continue reading →