Category Archives: Publications

Cells in Hypergravity .

Ever wondered how cells react when you fly them at 20g? Indeed they change their mechanical and other properties. This experiment, driven by Julia, is a ramp-up to our experiment flying on ISS. Hypergravity affects Cell Traction Forces of Fibroblasts … Continue reading

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Hemidesmosome mechanics, JCB 219, e201904137

Wang, W., A. Zuidema, L. te Molder, L. Nahidiazar, L. Hoekman, T. Schmidt, S. Coppola, and A. Sonnenberg. 2020. Hemidesmosomes modulate force generation via focal adhesions. The Journal of Cell Biology 219(2). [DOI] Abstract Hemidesmosomes are specialized cell-matrix adhesion structures … Continue reading

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Brillouin Imaging: BOE 5, 2202 –

Coppola, S., T. Schmidt, G. Ruocco, and G. Antonacci. 2019. “Quantifying cellular forces and biomechanical properties by correlative micropillar traction force and Brillouin microscopy”. Biomed. Opt. Express 10(5):2202-2212. [DOI] [pdf] Cells sense and respond to external physical forces and substrate … Continue reading

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GR mobility: JCS 132, 2019

Keizer VIP, Coppola S, Houtsmuller AB, Geverts B, van Royen ME, Schmidt T, Schaaf MJM. Repetitive switching between DNA-binding modes enables target finding by the glucocorticoid receptor. J Cell Sci. 2019 Feb 25;132(5). pii: jcs217455. [DOI] [pdf]

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hERG and cytoskeleton in PDAC: Cancer 23, 2019

Manoli S, Coppola S, Duranti C, Lulli M, Magni L, Kuppalu N, Nielsen N, Schmidt T, Schwab A, Becchetti A, Arcangeli A. The Activity of Kv 11.1 Potassium Channel Modulates F-Actin Organization During Cell Migration of Pancreatic Ductal Adenocarcinoma Cells. … Continue reading

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