Search
News
Latest Publications
Category Archives: Publications
Ever wanted to know about the mechanical stress inside and around a tumor? Here are the experiments.
Matrix stiffness affects spheroid invasion, collagen remodeling and the effective reach of stress into the ECM. Klara Beslmüller, Rick Rodrigues de Mercado, Gijsje H. Koenderink, Erik H.J. Danen, Thomas Schmidt The extracellular matrix (ECM) provides structural support to cells thereby … Continue reading
Posted in News, Publications, Research
Leave a comment
Paper on MechanoBiology of Chemoresistance.
Alessandro’s and Cecilia’s paper in which they investigated how chemoresistance modulates the mechanical phenotype of cells. Altered Mechanobiology of PDAC Cells with Acquired Chemoresistance to Gemcitabine and Paclitaxel. Alessandro Gregori, Cecilia Bergonzini, Mjriam Capula, Rick Rodrigues de Mercado, Erik … Continue reading
Posted in News, Publications
Leave a comment
Series of papers on PDAC
A series of three papers appeared this week in which we contributed towards therapeutic strategies in pancreatic cancer. A nice summary of results from our collaborative efforts ongoing for quite some years. That all those were accepted within one week … Continue reading
Paper on hexanematic order appeared in Nature Comm.
“Hexanematic crossover in epithelial monolayers depends on cell adhesion and cell density” Julia Eckert, Benoît Ladoux, René-Marc Mège, Luca Giomi & Thomas Schmidt Changes in tissue geometry during developmental processes are associated with collective migration of cells. Recent experimental and … Continue reading
Posted in News, Publications
Leave a comment
Integrin as prognostic marker
Integrin alpha-2 popped up in a screen of aggressive and chemoresistant PDAC cancers. In this study of Alessandro and Cecilia we validated the results we obtained in the RNA screen with various methods. Again we find a correlation between cell … Continue reading
Posted in News, Publications
Leave a comment
