Category Archives: Publications

From molecule to tissue.

Posted on 21-04-2021 by schmidt

Cell-cell and cell-matrix interactions are governed by interactions between individual molecules. But how does a tissue emerge from those localized and individual events? In this review we summarize our current understanding. Holding it together: when cadherin meets cadherin Arslan, F. … Continue reading →

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Pericyte mechanics.

Posted on 31-08-2020 by schmidt

Olga’s paper appeared in Stem Cell Reports, reporting on the particular mechanoresponse of pericytes, that might be related to their function. Fibronectin Patches as Anchoring Points for Force Sensing and Transmission in Human Induced Pluripotent Stem Cell-Derived Pericytes. Pericytes (PCs) … Continue reading →

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Cells in Hypergravity .

Posted on 09-04-2020 by schmidt

Ever wondered how cells react when you fly them at 20g? Indeed they change their mechanical and other properties. This experiment, driven by Julia, is a ramp-up to our experiment flying on ISS. Hypergravity affects Cell Traction Forces of Fibroblasts … Continue reading →

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Hemidesmosome mechanics, JCB 219, e201904137

Posted on 09-01-2020 by schmidt

Wang, W., A. Zuidema, L. te Molder, L. Nahidiazar, L. Hoekman, T. Schmidt, S. Coppola, and A. Sonnenberg. 2020. Hemidesmosomes modulate force generation via focal adhesions. The Journal of Cell Biology 219(2). [DOI] Abstract Hemidesmosomes are specialized cell-matrix adhesion structures … Continue reading →

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Brillouin Imaging: BOE 5, 2202 –

Posted on 04-04-2019 by schmidt

Coppola, S., T. Schmidt, G. Ruocco, and G. Antonacci. 2019. “Quantifying cellular forces and biomechanical properties by correlative micropillar traction force and Brillouin microscopy”. Biomed. Opt. Express 10(5):2202-2212. [DOI] [pdf] Cells sense and respond to external physical forces and substrate … Continue reading →

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