Category Archives: News

Molecule counting in STORM

Posted on 26-02-2022 by schmidt

We developed a novel methodology to count the number of molecules in a STORM image. That allowed us to address the stoichiometry of adhesion proteins in focal adhesions. It appeared that the stoichiometry in FAK is independent on the force … Continue reading →

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From molecule to tissue.

Posted on 21-04-2021 by schmidt

Cell-cell and cell-matrix interactions are governed by interactions between individual molecules. But how does a tissue emerge from those localized and individual events? In this review we summarize our current understanding. Holding it together: when cadherin meets cadherin Arslan, F. … Continue reading →

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Rick joined the team – welcome!

Posted on 31-08-2020 by schmidt

Rick joined our team as PhD student to investigate the role of mechanics and forces in metastasis. The project is embedded in a research program sponsored by an NWO EW-groot grant. Characterization of the Role of Cellular Forces in Cancer … Continue reading →

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Pericyte mechanics.

Posted on 31-08-2020 by schmidt

Olga’s paper appeared in Stem Cell Reports, reporting on the particular mechanoresponse of pericytes, that might be related to their function. Fibronectin Patches as Anchoring Points for Force Sensing and Transmission in Human Induced Pluripotent Stem Cell-Derived Pericytes. Pericytes (PCs) … Continue reading →

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Cells in Hypergravity .

Posted on 09-04-2020 by schmidt

Ever wondered how cells react when you fly them at 20g? Indeed they change their mechanical and other properties. This experiment, driven by Julia, is a ramp-up to our experiment flying on ISS. Hypergravity affects Cell Traction Forces of Fibroblasts … Continue reading →

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